乙酰胆碱酯酶抗體
產品名称： 乙酰(xian)胆碱酯(zhi)酶抗體
英文名称： Acetylcholinesterase antibody
產品编號： PR-1032
產品价格： null
產品產地： 陈苏
品牌商標： Hopebiot
更新時間： 2023-11-08T13:28:13
使用範围： ELISA,WB,IHC,ICC,IP,IF
- 聯系人 : 朱玉
- 地址 : 陈苏(su)省丹阳市吕(lv)城工業園
- 郵编 : 212300
- 所在區域 : 陈苏省
- 電話 : 189****1025 點擊查看
- 傳真 : 點擊查看
- 郵箱 : [email protected]
Background: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally.
Description: Rabbit polyclonal to Acetylcholinesterase
Immunogen: KLH conjugated synthetic peptide derived from Acetylcholinesterase
Specificity: ·Reacts with Human, Mouse, Cow, Dog and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 68 kDa;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;
·Immunocytochemistry: 1/200-500;
·ELISA: 1/500;
· Optimal working dilutions must be determined by the end user.