Anti-Active Rab11 Mouse Monoclonal Antibody
Anti-Active Rab11 Mouse Monoclonal Antibody是一種针對活性(xing)Rab11蛋白的小(xiao)鼠單克隆抗體產品。
Anti-Active Rab11 Mouse Monoclonal Antibody是一種特(te)异性识別活性Rab11蛋白的小(xiao)鼠單克隆抗體產品，
產品编號： 26919
產品价格： null
產品產地： 美國
品牌商標： NewEastbio
更新時間： null
使用範围： IP, IHC
武(wu)漢纽斯特生物技術有限公(gong)司
- 聯系人 :
- 地址 : 武漢市(shi)东湖新技術開发區光谷生物城B3-3栋2-3楼
- 郵编 : 430074
- 所在區域 : 湖北
- 電話 : 186****7297 點擊查看
- 傳真 : 點擊查看
- 郵箱 : [email protected]
| Catalog Number: 26919 |
| Gene Symbol: RAB11 |
| Description: Anti-Active Rab11 Mouse Monoclonal Antibody |
| Background: Small GTPases of the Rab-family are crucial elements of the machinery that controls membrane traffic. Rab11 has been shown to control traffic through the recycling endosome. |
| Immunogen: Recombinant full length protein of active Rab11 |
| Applications: IP, IHC |
| Recommended Dilutions: IP: 1 μg for 1~2 mg total cellular proteins IHC: 1:50~100 dilution |
| Concentration: 1 mg/ml |
| Host: mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG2b |
| Purity: Purified from ascites |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Anti-active Rab11 antibody recognizes active Rab11 from vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
| Immunoprecipitation/Western blot: |
|
Purified full-length Rab11 proteins were immunoprecipitated after treated with GDP (lane left) or GTPγS (lane right). Immunoprecipitation was done with the anti-active Rab11 monoclonal antibody (Cat. No. 26919). Immunoblot was with an anti-Rab5 polyclonal antibody (Cat. No. 21157). |
| Publications: |
| 1. VASP promotes TGF-β activation of hepatic stellate cells by regulating Rab11 dependent plasma membrane targeting of TGF-β receptors Hepatology Volume 61, Issue 1, pages 361–374, January 2015 |
| 2. Rab5 Activity Regulates GLUT4 Sorting into Insulin-Responsive and Non-Insulin-Responsive Endosomal Compartments: A Potential Mechanism for Development of Insulin Resistance Endocrinology. 2014 Sep;155(9):3315-28 |