Gα13-GTP 小鼠單抗/Anti-Gα13-GTP Mouse Monoclonal Antibody
Gα13-GTP 小鼠單抗是针對(dui)异三聚體 G 蛋白信號通路(lu)中活性(xing)型 Gα13 的特异(yi)性识別試剂，通過识(shi)別(bie) GTP 結合状態下的 Gα13 構象(xiang)變化來區分其活性状態。
Anti-Gα13-GTP Mouse Monoclonal Antibody 是一種(zhong)特异性识(shi)別Gα13蛋白GTP結合態的小鼠單克(ke)
產品编號： 26902
產品价格： null
產品產地： 美國
品牌商標： Neweast Biosciences
更新時間： null
使用範围： IP, IHC, IF
武漢費斯德生物科技有限公司
- 聯系人 :
- 地址 : 武漢东湖新(xin)技術開发區高(gao)新大道666號(hao)武漢國家生物產業基地項目（生物创新園）B.C.D區研发(fa)楼(lou)B3-3栋3楼
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- 所在區域 : 湖北
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- 郵箱 : [email protected]
| 货號: 26902 |
| 規格: 30 μL |
| 基因符號: Gna13 |
| 描述: Anti-Gα13-GTP Mouse Monoclonal Antibody |
| 背景介紹: Heterotrimeric G proteins are essential cellular signal transducers. Gα13 is one of the G proteins that could mediate cell migration and angiogenesis. Other biochemical and physiological functions of Gα13 are being explored. |
| 免疫原: Recombinant full length active Gα13 protein |
| 經過測試的應用: IP, IHC, IF |
| 推荐稀释比: IP: 1 μg for 1~2 mg total cellular proteins IHC, IF: 1:50-1:250 |
| 浓度: 1 mg/ml |
| 宿主: Mouse |
| 形式: Liquid |
| 克隆性: Monoclonal |
| 亚型: IgG2b |
| 純度: Purified from ascites |
| 防腐剂: No |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| 種屬反應性: Anti-active Gα13 monoclonal antibody recognizes active Gα13 of vertebrates. |
| 储存条件: Store at -20°C. Avoid repeated freezing and thawing |
免疫沉淀/蛋白質印迹:  IP/WB analysis of active Gα13 proteins. Purified Gα13 proteins were treated with GDP (lane 1) or GTPGTPγS (lane 2). After immunoprecipitation with anti-active Gα13-GTP mouse monoclonal antibody (Cat. # 26902), these proteins were separated by SDS/PAGE and western blotted with anti- Gα13 mouse monoclonal antibody (Cat. # 26004). |
Immunohistochemistry:  Staining of MEF cells (treated with PDGF) with anti- Gα13-GTP monoclonal antibody showing the localization of Gα13-GTP in the leading edge of migrating cells. |